Research Working Group
Dr. Janet Crane
Janet Crane, MD is an Associate Professor at Johns Hopkins University (JHU) with a joint appointment in Pediatric Endocrinology and the Orthopedic Surgery Center for Musculoskeletal Research. She serves as the director of the Pediatric Bone Health Clinic program at JHU and as a Clinical Associate at the Kennedy Krieger Institute Center for Genetic Muscle Disorders and Bone Disorders Program.
Dr. Crane’s research mission is to understand hormonal signaling pathways that regulate bone vasculature and sensory innervation in relationship to skeletal disorders and how these signaling pathways can be manipulated by pharmaceutical drug targets. She adapts this knowledge to develop treatment recommendations for children with bone disorders, specifically skeletal fragility, osteoporosis, and metabolic bone disease. Dr.Crane received the Young Physician-Scientist Award from the American Society for Clinical Investigation in 2016 and receives research grant funding from the U.S. National Institutes of Health and Department of Defense. Dr. Crane is a member of the Osteoporosis Prevention Working Group and the Growth and Puberty Working Group within OPTIMZE DMD.
Fun fact: Dr. Crane enjoys traveling and has set foot in 44 US states and 4 continents. Contact information : jcrane2@jhmi.edu
Dr. David R. Webber
Dr. David Weber is an attending Physician in Pediatric Endocrinology and the Associate Professor of Pediatrics, The Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania. Dr. Weber is the Medical Director of the Center for Bone Health and Research Director of the Nutrition and Growth Lab at CHOP. He is passionate about improving the endocrine and bone health care of people with DMD and has participated in multi-disciplinary neuromuscular clinics for over a decade, first at the University of Rochester and now at CHOP.
Dr. Weber’s research group is actively studying the impact of DMD and other chronic diseases on bone health. He also has an interest in rare disorders of bone mineral metabolism and is currently working on studies in conditions includingENPP1 and CYP24A1 deficiency.
Dr. Weber is currently co-chair of the Bone and Mineral Special Interest Group of the Pediatric Endocrine Society and a member of the Professional Practice Committee of the American Society of Bone and Mineral Research (ASBMR). Dr. Weber is a member of the Steering Committee, Co-Chair of the Adrenal Working Group, and a member of the Osteoporosis Working Group.